Can the satiety mechanism in PWS be controlled?

Kate McAllister and colleagues at the Cambridge University, UK, have been involved in researching the brain's ability to appreciate satiety.  This video clip  http://www.youtube.com/watch?v=ofgjtGra3I8  shows an interesting perspective on looking at how the on-off switch for fullness, particularly in Prader-Willi Syndrome, might be regulated.  Much research has been done on looking at the genetics of obesity, and the genetics of PWS could well hold the key to discovering why the desire to eat over-rides any control mechanism. 

Please have a look at this YouTube clip on research being done by Cambridge University on monitoring the brain's ability to appreciate satiety. If they can implement the conclusion they are suggesting, it is very exciting news.  To contact Kate directly: km511@medschl.cam.ac.uk